Refractory Acute Myeloid Leukemia (AML) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Relapse Acute myeloid leukemia (RAML) is the most
common type of leukemia in adults, yet continues to have the lowest survival
rate of all leukemias. Although rates have improved remarkably in the younger
age group, the prognosis in older patients continues to be very poor.
Chemotherapeutic agents, such as alkylating agents and topoisomerase II
inhibitors, have been reported to increase the incidence of AML. A number of
other substances have been linked to an increased risk of AML. Chronic exposure
to certain chemicals clearly shows an increased risk for the development of
AML. Benzene is the best-studied and most widely used potentially a leukemogenic
agent.
·
Acute myeloid leukemia
(AML) is a malignant disorder of the bone marrow which is characterized by the
clonal expansion and differentiation arrest of myeloid progenitor cells. The
age-adjusted incidence of AML is 4.3 per 100,000 annually in the United States
(US).
· It has been estimated that approximately 22,850
adults diagnosed with AML in 2020, AML accounts for the highest percentage
(62%) of leukemic deaths.
The competitive
landscape of Refractory Acute Myeloid Leukemia (AML) includes country-specific
approved as well as pipeline therapies. Any asset/product-specific designation
or review and Accelerated Approval are being tracked and supplemented with
analyst commentary.
KOLs insights of Refractory
Acute Myeloid Leukemia (AML) across 8 MM market from the center of Excellence/
Public/ Private hospitals participated in the study. Insights around current
treatment landscape, epidemiology, clinical characteristics, future treatment
paradigm, and Unmet needs.
Refractory
Acute Myeloid Leukemia (AML) Market
Forecast: Patient Based Forecast Model (MS. Excel Based Automated
Dashboard) which Data Inputs with sourcing, Market Event, and Product Event,
Country specific Forecast Model, Market uptake and patient share uptake,
Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario,
Summary, and Insights.
S. No Asset Company Stage
1 CPI-613 Rafael
Pharmaceuticals Inc. Phase 3
2 Fosciclopirox CicloMed
LLC Phase 2
3 Pazopanib Novartis Phase 2
4 DSP-5336 Sumitomo
Dainippon Pharma Oncology, Inc Phase
2
5 LAVA-051 Lava
Therapeutics Phase 2
6 Liposomal Annamycin Moleculin
Biotech, Inc. Phase 2
7 IMGN632 ImmunoGen,
Inc. Phase 2
8 GTB-3550 TriKE® GT
Biopharma, Inc. Phase 2
9 AB8939 AB Science SA Phase 1
10 ONO-7475 Ono
Pharmaceutical Co. Ltd Phase 2
Continued
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