Relapsed or Refractory Peripheral T-Cell Lymphoma (r/r PTCL) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
Peripheral T-cell lymphoma (PTCL) is a rare group of typically fast-growing Non-Hodgkin's Lymphomas (NHL) that originates from mature T-cells and natural killer (NK) cells, which are mature-stage white blood cells. This subtype of NHL specifically affects T-cells and occurs when these cells develop and proliferate abnormally. Patients diagnosed with PTCL often face a grim prognosis characterized by multiple relapses and resistance to initial treatment. Relapsed or Refractory Peripheral T-cell lymphoma refers to a condition where the disease reappears or grows again after a period of remission (relapsed) or when the lymphoma does not respond to treatment (refractory), meaning that the cancer cells continue to grow, or when the response to treatment does not last very long. Median overall survival for relapsed patients had a longer survival period at 29.1 months compared to refractory patients with only 12.3 months. One-year survival rates are influenced by the response to the initial therapy, with 84% survival among relapsed patients and 52% among refractory patients. Among all relapsed and refractory patients, those achieving a complete response to second-line therapy had a notably extended survival compared to those with a partial response or worse. Recently, the FDA approved four next-generation drugs (pralatrexate, romidepsin, brentuximab vedotin, and belinostat) for treating relapsed and refractory PTCL based on their response rates. However, none of these agents led to improvements in overall survival. The European Medicines Agency (EMA) declined to approve both pralatrexate and romidepsin due to a lack of clear clinical benefits, and belinostat is not licensed in Europe despite being granted orphan designation status by the EMA. Brentuximab vedotin is the only drug approved by the EMA to treat relapsed or refractory systemic ALCL, primarily due to a more favorable benefits-to-risks ratio.
Thelansis’s
“Relapsed or Refractory Peripheral T-Cell Lymphoma (r/r PTCL) Market Outlook,
Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033"
covers disease overview, epidemiology, drug utilization, prescription share
analysis, competitive landscape, clinical practice, regulatory landscape,
patient share, market uptake, market forecast, and key market insights under
the potential Relapsed or Refractory Peripheral T-Cell Lymphoma (r/r PTCL)
treatment modalities options for eight major markets (USA, Germany, France,
Italy, Spain, UK, Japan, and China).
KOLs insights of Relapsed or
Refractory Peripheral T-Cell Lymphoma (r/r PTCL) across 8 MM market from the
centre of Excellence/ Public/ Private hospitals participated in the study.
Insights around current treatment landscape, epidemiology, clinical
characteristics, future treatment paradigm, and Unmet needs.
Relapsed
or Refractory Peripheral T-Cell Lymphoma (r/r PTCL) Market Forecast Patient
Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs
with sourcing, Market Event, and Product Event, Country specific Forecast
Model, Market uptake and patient share uptake, Attribute Analysis, Analog
Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice
has been established based on a deep understanding of the pharma/biotech
business environment to provide an optimized support system to all levels of
the decision-making process. It enables business leaders in forward-thinking
and proactive decision-making. Thelansis supports scientific and commercial
teams in seamless CI support by creating an AI/ ML-based technology-driven
platform that manages the data flow from primary and secondary sources.
Tags: Relapsed
or Refractory Peripheral T-Cell Lymphoma (r/r PTCL), Relapsed or Refractory
Peripheral T-Cell Lymphoma (r/r PTCL) market outlook,
Relapsed or Refractory Peripheral T-Cell Lymphoma (r/r PTCL) competitive landscape, Relapsed or Refractory
Peripheral T-Cell Lymphoma (r/r PTCL) market
forecast, Thelansis, Primary market research, KOL insights, Competitive
Intelligence (CI)
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